Literature summary for 3.4.21.B10 extracted from

Scarisbrick, I.A.; Epstein, B.; Cloud, B.A.; Yoon, H.; Wu, J.; Renner, D.N.; Blaber, S.I.; Blaber, M.; Vandell, A.G.; Bryson, A.L.
Functional role of kallikrein 6 in regulating immune cell survival (2011), PLoS ONE, 6, e18376.

Search for more literature for 3.4.21.B10

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in a baculovirus/insect system	Mus musculus
expressed in a baculovirus/insect system	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Mus musculus
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
JURKAT cell	-	Homo sapiens	-
splenocyte	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
kallikrein 6	-	Mus musculus
kallikrein 6	-	Homo sapiens
KLK6	-	Mus musculus
KLK6	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	KLK6 promotes lymphocyte survival by a mechanism that depends in part on activation of protease-activated receptor 1. Recombinant KLK6 significantly reduces cell death under resting conditions and in response to camptothecin, dexamethasone, staurosporine and Fas-ligand. Immune cell survival promoting effects of KLK6 include both T and B lymphocytes and involve up regulation of the pro-survival protein B-cell lymphoma-extra large and inhibition of the pro-apoptotic protein Bcl-2-interacting mediator of cell death	Mus musculus
physiological function	KLK6 promotes lymphocyte survival by a mechanism that depends in part on activation of protease-activated receptor 1. Recombinant KLK6 significantly reduces cell death under resting conditions and in response to camptothecin, dexamethasone, staurosporine and Fas-ligand. Immune cell survival promoting effects of KLK6 include both T and B lymphocytes and involve up regulation of the pro-survival protein B-cell lymphoma-extra large and inhibition of the pro-apoptotic protein Bcl-2-interacting mediator of cell death	Homo sapiens

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Release 2023.1 (January 2023)